It looks like you're new here. If you want to get involved, click one of these buttons!
div>Sleep variables were collected from overnight polysomnography. The Pearson's correlations were used to evaluate the associations between daytime EE and sleeping EE for each sleeping condition, after controlling for gender, age and body mass index (BMI). Results: Daytime EE was significantly higher than sleeping EE, p?<?0.001. However, EE during the day or during the sleep period was not significantly different between sleeping conditions. A significant positive correlation between daytime <a href="http://www.selleckchem.com/screening/pi3k-signaling-inhibitor-library.html">PI3K Inhibitor Library purchase and sleeping EE across the eight sleeping conditions was observed (r ranged from 0.524 to 0.829, p?<?0.05). In addition, in 4 out of 8 sleeping conditions, daytime EE was positively correlated with SWS (r ranged from 0.483 to 0.665, p?<?0.05). Conclusion: Higher energy expanded during the day predicts higher level of energy expanded during sleep. Higher daytime energy demand also predicts longer SWS duration at least in four sleeping conditions. These findings suggest that a link exists between daytime metabolic demand and sleeping energy metabolism, and lend support for the restorative function of sleep. HARUKI SEKIGUCHI, KOUJI NARUI, YUJI INOUE, ARISA WADA, YAGISAWA, TAKASHI YAGISAWA. YASUNOBU HASHIMOTO, YOSHIKO MAEDA, FUJIO TATSUMI, MAYUMI SUZUKI, KEN SHIMAMOTO, KAZUHIRO YAMAGUCHI, MASATOSHI KAWAN Comprehensive <a href="https://en.wikipedia.org/wiki/Fossariinae">Fossariinae Medical Center of Sleep Disorders, Aoyama Hospital, Tokyo Women's Medical University, Japan Objectives: Erectile dysfunction (ED) is one of the important complications in patients with sleep apnea syndrome (SAS). However, risk factors related to ED as well as the efficacy of continuous positive airway pressure (CPAP) therapy on improving ED have not been established in Japanese subjects. Methods: We conducted a retrospective population-based study Sunitinib clinical trial of Japanese subjects linking questionnaire data with characteristics of patients hospitalized (170 males, age: 49?��?12.3 years) due to SAS diagnosis by polysomnography. SAS was diagnosed as AHI?>?5 and ED diagnosed by an International Index of Erectile Function (IIEF)-5 score <22. Thirty patients answered IIEF5 twice before and at 6 months after CPAP treatment. We analyzed the correlation between ED and potential explanatory variables including age, BMI, AHI, HTN, DM, dementia, dyslipidemia, and benign prostatic hyperplasia. We also investigated predictors judging the efficacy of CPAP on improvement of ED. Results: Baseline BMI and AHI were, respectively, 27.3?��?4.0?kg/m2 and 43.1?��?27.8 /hr in this study population. ED was observed in 59.4% (101/170) of the patients. DM and HTN were found to be risk factors for ED (odds ratio: 2.89, P?<?0.001, OR: 3.47, P?<?0.01, respectively). Multivariate analysis revealed that DM (OR: 4.4, P?<?0.001) was a unique, independent risk factor for ED. After 6 month CPAP treatment, IIEF5 scores significantly decreased in 53.3% (16/30) of ED patients (3.4?��?2.3, P?<?0.001).