The Entire Technological Invention Behind Resiquimod
  • J Neurotrauma 2007;24(Suppl. 11):1675�C86. [3] Garland DE, Hanscom DA, Keenan MA, Smith C, Moore T. Resection of heterotopic ossification in the adult with head trauma. J Bone Joint Surg Am 1985;67(Suppl. 1):1261�C9. [4] Genet F, Jourdan C, Schnitzler A, Lautridou C, Guillemot D, Judet T. Troublesome heterotopic ossification after central nervous system damage: a survey of 570 surgeries. PLoS One 2011;6(Suppl. 1):e16632. ""Background and purpose.�C Heterotopic ossifications (HOs) are a common secondary complication of central neurological system (CNS) damage. This ectopic ossification reduces range of motion until ankylosis or vessel and nerve compression occur. HOs are frequently described after Traumatic Brain Injury, Spinal Cord Injury and in a much smaller proportion after Stroke. HOs commonly happen on the paretic side and mainly after hemorrhagic stroke. The aims of this study are to assess the features of HO after stroke in a large sample of patients and to determine whether hemorrhagic stroke increases the risk of HO. Methods.�C Twenty-four stroke patients with 31 troublesome HO were retrospectively studied between 1993 and 2009 in our institution. They were each matched with four controls i.e. 96 stroke patients without troublesome HO. Matching criteria were age (��?3.5 years) and sex. Results.�C The mean age at time of stroke was 42.8?��?7.32 years (from 31.8 to 54.8) for the case subgroup and 44.3?��?8.69 years (28.6�C64.8) for the control group. Delay from stroke to surgery for HO excision was 80.9?��?92.5 months (from 13.5 to 39.87). A significant association between hemorrhagic stroke and HO development was found (OR?=?2.99 (95% CI: 1.14�C7.88); P?<?0.05), but not ischemic stroke. By including all the matching and risk factors in the model, this relationship <a href="">Resiquimod was no longer found (adjusted OR?=?2.45 (95% CI: 0.69�C8.68); P?=?0.17). Conclusion.�C Hemorrhagic stroke does not seem be related to an increased risk of troublesome HO. ""Introduction.�C La douleur et l��?d��me postop��ratoires limitent la mobilisation et doivent ��tre trait��s. Le recours �� un bloc p��ri nerveux par cath��ter brachial est justifi�� dans de nombreux cas, notamment pour les douleurs postop��ratoires mod��r��es �� s��v��res dans le cadre d��une analg��sie multimodale. L��objectif de ce travail est de montrer l��int��r��t de l��utilisation des cath��ters nerveux apr��s arthrolyse du coude sur les r��sultats fonctionnels apr��s r����ducation. Patients et m��thodes.�C ?tude descriptive, transversale et prospective (2004�C2011) portant sur 31?arthrolyses du coude suivies en MPR pour r����ducation postop��ratoire?: groupe 1?: six patients (avec cath��ter)?; groupe2?: 25?patients (sans cath��ter). M��thodes d����valuation?: EVA?; ROM?; ��valuation fonctionnelle?: alimentation, toilette, ��criture, DASH. R��sultats.�C L��?ge moyen?: 24?ans (10�C40), pr��dominance masculine (77?% hommes), les deux principales indications d��arthrolyse?=?raideurs post traumatique et POA.

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