Results? There was no difference in knowledge between the two groups at baseline. Both groups demonstrated significant gains in knowledge after intervention (P?<?0.0001). Group B (Web/podcast) showed a significantly greater increase in knowledge (P?<?0.05) than group A (lecture). Preintervention subjective assessment of knowledge rated by the students showed no difference between the groups. Both groups of students were equally satisfied with the educational method. Conclusion? E-learning supplemented with a podcast results in greater knowledge acquisition when compared with a traditional lecture, without a loss of satisfaction with teaching. Using augmented Web-based educational tools reduces demands on teaching time with no decrease in quality for selected <a href="http://www.selleckchem.com/products/3-methyladenine.html
">3-Methyladenine research buy parts of the curriculum. ""Bowel cancer screening provides an opportunity to re-evaluate the therapeutic strategy for rectal cancer. In recent years there has been a rapid reduction in rectal cancer disease-associated mortality, but treatment-related morbidity and mortality remain high [1, 2]. Long-term bowel, bladder and sexual dysfunctions are frequent complications of radical surgery for rectal cancer [3, 4]. Permanent stomas are required in perhaps one-fifth of cases. The 30-day mortality for all rectal cancer surgery performed within the UK National Health Service (NHS) is 4.6% . Screening using the faecal occult blood test (FOBT) Ceftiofur
identifies a high proportion of cases of rectal cancer at an early stage. In 2009, approximately 25% of the UK's 13?970 newly diagnosed rectal tumours were Dukes A (T1/2N0). Incorporation of flexible sigmoidoscopy, a more sensitive tool than FOBT, into the national screening programme from 2014 will further promote early diagnosis . Although Dukes A tumours are generally small and localized, standard treatment dictates removal of the entire organ by radical surgery. Radical surgery achieves complete rectal and mesorectal Selleckchem Sunitinib
excision, providing definitive information about the T stage and local nodal metastasis. If no involved nodes are found then there is little risk of regional recurrence and a diminished risk of systemic relapse. There is no lymph node involvement (N0) in 80�C85% of T1 and T2 rectal cancers . Hence, routine lymph node dissection in these patients is over-treatment and could potentially be avoided. In the present issue of Colorectal Disease, Sajid et?al.  have examined this contentious area. They performed a meta-analysis of 942 cases from 10 studies, comparing conventional treatment of pT1 and pT2 rectal cancer by radical surgery with an organ-preserving approach using either transanal endoscopic microsurgery (TEMS) or chemoradiation followed by TEMS. Five papers contained a randomized comparison and the other five employed retrospective case controls. The authors acknowledge that the quality of all studies was only moderate to low at best.