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""Increased physical activity can reduce the incidence of cardiovascular disease and the mortality rate. In contrast, a prolonged heart rate corrected-QT (QTc) interval is associated with an increased risk of arrhythmias, sudden cardiac death and coronary artery disease. The present cross-sectional study was designed to clarify the association between the physical activity level and the QTc interval in older adults. The participants included 586 older adults (267 men and 319 women, age 71.2?��?4.7?years) without a history of cardiovascular selleckchem disease, who were taking cardioactive drugs. Electrocardiography was recorded with a standard resting 12-lead electrocardiograph, while the QTc interval was calculated according to Hodges' formula. The physical activity level was assessed using a triaxial accelerometer. The participants were divided into four categories, which were defined equally quartile distributions of the QTc interval. After adjusting for age, body mass index, waist circumference and the number of steps, the time spent in inactivity was higher and the time spent in light physical activity 3-Methyladenine was significantly lower in the longest QTc interval group than in the shortest QTc interval group in both sexes (P?<?0.05, respectively). However, there were no significant differences in the time spent in moderate and vigorous physical activities among the four groups in either sex. These results suggest that a decreased physical activity level, especially inactivity and light intensity physical activity, were associated with QTc interval in older adults. Geriatr Gerontol Int 2014; ���: ���C���. ""To evaluate the impact of hearing aid (HA) fittings among elderly patients through the Hearing Handicap Inventory for the Elderly (HHIE). The present study was carried out with 125 hearing-impaired individuals over aged 65 years in the northern region of Minas Gerais, Brazil. The instrument used was the HHIE self-assessment questionnaire. HHIE were completed before and after HA fittings. Data were analyzed using the non-parametric Wilcoxon test and the McNemar ��2-test. There were significant decreases in general, social and emotional handicap after HA use (P?<?0.001). The percentage <a href="http://www.selleckchem.com/products/PF-2341066.html">http://www.selleckchem.com/ of patients with severe hearing handicap decreased from 45.6% to 8.8% with HA use. The greatest difficulty reported by respondents, both before and after HA use, was ��hearing when someone whispers��. Although HA use significantly improves the hearing handicap, some older adults still maintain social and emotional limitations. The HHIE instrument can be a great ally in helping professionals understand and rehabilitate the difficulties that remain after amplification. Geriatr Gerontol Int 2014; ���: ���C���. ""The care needs of people with Parkinson's disease (PD) are poorly understood.
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